Citation:
Odelia Tepper, Zheng, Hongchao , Appella, Daniel H. , and Yavin, Eylon . 2021. “Cyclopentane Fit-Pnas: Bright Rna Sensors”. Chemical Communications, 57, 4, Pp. 540–543. doi:10.1039/D0CC07400D.
Abstract:
Cyclopentane modified FIT-PNA (cpFIT-PNA) probes are reported as highly emissive RNA sensors with the highest reported brightness for FIT-PNAs. Compared to FIT-PNAs, cpFIT-PNAs have improved mismatch discrimination for several pyrimidine-pyrimidine single nucleotide variants (SNVs).